This is an important text for a still-emerging field of Biology, relating the embryo to its environment. Intersecting numerous disciplines in the Biological and Life Sciences, the authors have provided coverage in which the molecular biology of epigenetic development meets and interacts with the evolutionary aspects of phenotypic plasticity.
'Overall, a masterful synthesis! It's one of those things that makes one say, "Damn, I wish I had written that!"' - Fred Nijhout, Duke University, USA
'A unique, thought-provoking, and clearly written treatment, at the molecular level, of the environment's influence on embryonic development and the paths of evolutionary change.' - John Gerhart, University of California, Berkeley, USA
'This is an incredible piece of work, and something that is sorely needed, right now.' - Mary Tyler, University of Maine, USA
'This is an extraordinary work … first-class conceptually and pedagogically.' - John Beatty, University of British Columbia, Canada
PART I: ENVIRONMENTAL SIGNALS AND NORMAL DEVELOPMENT
The Environment as a Normal Agent in Producing Phenotypes
How Agents in the Environment Effect Molecular Changes in Development
Developmental Symbiosis: Co-Development as a Strategy for Life
Embryonic Defenses: Survival in a Hostile World
PART II: ECOLOGICAL DEVELOPMENTAL BIOLOGY AND DISEASE STATES
Teratogenesis: Environmental Assaults on Development
Endocrine Disruptors
The Epigenetic Origin of Adult Diseases
PART III: TOWARD A DEVELOPMENTAL EVOLUTIONARY SYNTHESIS
The Modern Synthesis: Natural Selection of Allelic Variation
Evolution through Developmental Regulatory Genes
Environment, Development, and Evolution: Toward a New Synthesis
CODA: Philosophical Concerns Raised by Ecological Developmental Biology
APPENDX A: Lysenko, Kammerer, and the Truncated Tradition of Ecological Developmental Biology
APPENDIX B: The Molecular Mechanisms of Epigenetic Change
APPENDIX C: Writing Development Out of the Modern Synthesis
APPENDIX D: Epigenetic Inheritance Systems: The Inheritance of Environmentally Induced Traits
SCOTT A. GILBERT, Howard A. Schneiderman Professor of Biology, Martin Laboratories, Swarthmore College, Swarthmore, PA, USA
DAVID EPEL, Jane & Marshall Steel Jr. Professor in Marine Sciences, Hopkins Marine Station, Stanford University, Monterey, CA, USA
Description
This is an important text for a still-emerging field of Biology, relating the embryo to its environment. Intersecting numerous disciplines in the Biological and Life Sciences, the authors have provided coverage in which the molecular biology of epigenetic development meets and interacts with the evolutionary aspects of phenotypic plasticity.
Reviews
'Overall, a masterful synthesis! It's one of those things that makes one say, "Damn, I wish I had written that!"' - Fred Nijhout, Duke University, USA
'A unique, thought-provoking, and clearly written treatment, at the molecular level, of the environment's influence on embryonic development and the paths of evolutionary change.' - John Gerhart, University of California, Berkeley, USA
'This is an incredible piece of work, and something that is sorely needed, right now.' - Mary Tyler, University of Maine, USA
'This is an extraordinary work … first-class conceptually and pedagogically.' - John Beatty, University of British Columbia, Canada
Contents
PART I: ENVIRONMENTAL SIGNALS AND NORMAL DEVELOPMENT
The Environment as a Normal Agent in Producing Phenotypes
How Agents in the Environment Effect Molecular Changes in Development
Developmental Symbiosis: Co-Development as a Strategy for Life
Embryonic Defenses: Survival in a Hostile World
PART II: ECOLOGICAL DEVELOPMENTAL BIOLOGY AND DISEASE STATES
Teratogenesis: Environmental Assaults on Development
Endocrine Disruptors
The Epigenetic Origin of Adult Diseases
PART III: TOWARD A DEVELOPMENTAL EVOLUTIONARY SYNTHESIS
The Modern Synthesis: Natural Selection of Allelic Variation
Evolution through Developmental Regulatory Genes
Environment, Development, and Evolution: Toward a New Synthesis
CODA: Philosophical Concerns Raised by Ecological Developmental Biology
APPENDX A: Lysenko, Kammerer, and the Truncated Tradition of Ecological Developmental Biology
APPENDIX B: The Molecular Mechanisms of Epigenetic Change
APPENDIX C: Writing Development Out of the Modern Synthesis
APPENDIX D: Epigenetic Inheritance Systems: The Inheritance of Environmentally Induced Traits
Authors
SCOTT A. GILBERT, Howard A. Schneiderman Professor of Biology, Martin Laboratories, Swarthmore College, Swarthmore, PA, USA
DAVID EPEL, Jane & Marshall Steel Jr. Professor in Marine Sciences, Hopkins Marine Station, Stanford University, Monterey, CA, USA
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