In the new edition of Biochemistry, instructors will see the all the hallmark features that made this a consistent bestseller for the undergraduate biochemistry course: exceptional clarity and concision, a more biological focus, cutting-edge content, and an elegant, uncluttered design. Accomplished in both the classroom and the laboratory, coauthors Jeremy Berg and John Tymoczko draw on the field's dynamic research to illustrate its fundamental ideas. The 6th edition features new chapters, a strong emphasis on biological relevance and new tools for molecular visualisation. 

 
'An excellent textbook which combines basic principles of biochemistry with clinical situations and pathophysiology.' - J M Land - Clinical National Hospital London
 
'A superby presented book - in keeping with the high standard of the previous editions. A must for all biochemistry students.' - R E Glass - Nottingham University

'The integration of evolution makes it the most exciting and revolutionary biochemistry text to appear since 1970.' - James F. Koerner, University of Minnesota

'I really like the chemical and structural approach to describing the changes in the molecules and the energetics involved.' - Paul Craig, Rochester Institute of Technology
'Another fantastic book.' - Gunnar Hansson - Gothenburg University
 
'An excellent textbook for students taking biochemistry. ' - P Maskrey - Northumbria University
 
'Nice updates, nice web resource. The organisation of some topics has improved (i.e. Glycolysis and Gluconeogenesis in the same chapter).' - Dr Lorenzo Frigerio, University of Warwick

'An excellent revision. I like the use of structures throughout.' - R C Ford - Manchester University

'Much improved - good cover of genetics and metabolism.' - A Nicolaou - Bradford University

PART I: THE MOLECULAR DESIGN OF LIFE
Biochemistry: An Evolving Science
Protein Composition and Structure
Exploring Proteins and Proteomes
DNA, RNA and the Flow of Genetic Information
Exploring Genes and Genomes
Exploring Evolution and Bioinformatics
Hemoglobin: Portrait of a Protein in Action
Enzymes: Basic Concepts and Kinetics
Catalytic Strategies
Regulatory Strategies
Carbohydrates
Lipids and Cell Membranes
Membrane Channels and Pumps
Signal Transduction Pathways

PART II: TRANSDUCING AND STORING ENERGY
Metabolism: Basic Concepts and Design
Glycolysis and Gluconeogenesis
The Citric Acid Cycle
Oxidative Phosphorylation
The Light Reactions of Photosynthesis
The Calvin Cycle and the Pentose Phosphate Pathway
Glycogen Metabolism
Fatty Acid Metabolism
Protein Turnover and Amino Acid Catabolism

PART III: SYNTHESIZING THE MOLECULES OF LIFE
The Biosynthesis of Amino Acids
Nucleotide Biosynthesis
The Biosynthesis of Membrane Lipids and Steroids
The Integration of Metabolism
DNA Replication, Repair and Recombination
RNA Synthesis and Processing
Protein Synthesis
The Control of Gene Expression

PART IV: RESPONDING TO ENVIRONMENTAL CHANGES
Sensory Systems
The Immune System
Molecular Motors
Drug Development

JEREMY M. BERG is Director of the National Institute of General Medical Sciences at the National Institute of Health, USA. He is the recipient of the American Chemical Society Award in Pure Chemistry (1994), the Eli Lilly Award for Fundamental Research in Biological Chemistry (1995), the Maryland Outstanding Young Scientist of the Year (1995) and the Harrison Howe Award (1997).

JOHN L. TYMOCZKO is the Towsley Professor of Biology at Carleton College, USA, where he has taught since 1976.

LUBERT STRYER is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University, USA, where he has been on the faculty since 1976. He was elected to the National Academy of Sciences in 1984.