25 years and still going strong! Lehninger Principles of Biochemistry has been a classroom favourite since its first edition. It is the classic introduction to biochemistry that brings clarity and coherence to an often unwieldy discipline, a textbook on the field's classic core, always made fresh by combining the field's definitive advances with an admirable ability to reach students. In addition to its content updates throughout, the fifth edition also provides updated pedagogy that supports lecturers in addressing key challenges in teaching the biochemistry course.

The Foundations of Biochemistry
PART I: STRUCTURE AND CATALYSIS
Water
Amino Acids, Peptides, and Proteins
The Three-Dimensional Structure of Proteins
Protein Function
Enzymes
Carbohydrates and Glycobiology
Nucleotides and Nucleic Acids
DNA-Based Information Technologies
Lipids
Biological Membranes and Transport
Biosignaling
PART II: BIOENERGETICS AND METABOLISM
Principles of Bioenergetics
Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
Principles of Metabolic Regulation: Glucose and Glycogen
The Citric Acid Cycle
Fatty Acid Catabolism
Amino Acid Oxidation and the Production of Urea
Oxidative Phosphorylation and Photophosphorylation
Carbohydrate Biosynthesis in Plants and Bacteria
Lipid Biosynthesis
Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
Hormonal Regulation and Integration of Mammalian Metabolism
PART III: INFORMATION PATHWAYS
Genes and Chromosomes
DNA Metabolism
RNA Metabolism
Protein Metabolism
Regulation of Gene Expression

DAVID L. NELSON, University of Wisconsin-Madison, USA

MICHAEL M. COX, University of Wisconsin-Madison, USA