This book describes the essential aspects of enantioselective catalysis in a clear, logical fashion, with chapters organized by concept rather than by reaction type. Each concept in Fundamentals of Asymmetric Catalysis is supported by carefully selected examples of a wide range of catalysts, reactions and reaction mechanisms.
'This book is a great tool and "go to" book for students and practitioners interested in Asymmetric Synthesis.' - Mukund Sibi, North Dakota State University, USA
'This is an impressive piece of scholarship that will be welcomed by the catalysis community.' - Jeffrey S. Johnson, University of North Carolina, USA
'In summary, this fascinating book captures the diversity and applicability of an area of research that has emerged as one of the fastest growing fields in organic chemistry. As a text that addresses the major concepts of asymmetric catalysis, it could serve as an excellent aid for a university course on asymmetric catalysis. Hence, this book is destined to become a firm favourite for advanced graduate students. Additionally, the book can be recommended to all scientists in academia and industry with an interest in asymmetric catalysis - as a source of information and for references. As a potential standard work on this subject, Fundamentals of Asymmetric Catalysis is worth the price and should appear on many bookshelves and in many libraries.' - Stefan F. Kirsch, Angewandte Chemie International Edition
Foreword
Introduction to Fundamentals of Asymmetric Catalysis
Modes of Asymmetric Induction
Lewis Acid and Lewis Base Catalysis
Beyond Lewis Acid and Lewis Base Catalyzed Activation
Asymmetric Induction in Enantioselective Catalysis
Nonclassical Catalyst Substrate Interactions
Chiral Poisoning, Chiral Activation, and Screening Achiral Ligands
Kinetic Resolution
Parallel Kinetic Resolution
Dynamic Kinetic Resolution and Dynamic Kinetic Asymmetric Transformations
Desymmetrization Reactions
Nonlinear Effects, Autocatalysis, and Autoinduction
Bifunctional, Dual, and Multifunctional Catalyst Systems
Asymmetric Catalysis with Enantiopure Substrates: Double Diastereoselection
Multistep Asymmetric Catalysis
Supported Chiral Catalysts
Applications of Asymmetric Catalysis in Synthesis
Appendix: Terms & Enantioselective Processes in Asymmetric Catalysis
Index
PATRICK J. WALSH is a Professor of Chemistry at University of Pennsylvania, USA
MARISA C. KOZLOWSKI is a Professor of Chemistry at University of Pennsylvania, USA
Description
This book describes the essential aspects of enantioselective catalysis in a clear, logical fashion, with chapters organized by concept rather than by reaction type. Each concept in Fundamentals of Asymmetric Catalysis is supported by carefully selected examples of a wide range of catalysts, reactions and reaction mechanisms.
Reviews
'This book is a great tool and "go to" book for students and practitioners interested in Asymmetric Synthesis.' - Mukund Sibi, North Dakota State University, USA
'This is an impressive piece of scholarship that will be welcomed by the catalysis community.' - Jeffrey S. Johnson, University of North Carolina, USA
'In summary, this fascinating book captures the diversity and applicability of an area of research that has emerged as one of the fastest growing fields in organic chemistry. As a text that addresses the major concepts of asymmetric catalysis, it could serve as an excellent aid for a university course on asymmetric catalysis. Hence, this book is destined to become a firm favourite for advanced graduate students. Additionally, the book can be recommended to all scientists in academia and industry with an interest in asymmetric catalysis - as a source of information and for references. As a potential standard work on this subject, Fundamentals of Asymmetric Catalysis is worth the price and should appear on many bookshelves and in many libraries.' - Stefan F. Kirsch, Angewandte Chemie International Edition
Contents
Foreword
Introduction to Fundamentals of Asymmetric Catalysis
Modes of Asymmetric Induction
Lewis Acid and Lewis Base Catalysis
Beyond Lewis Acid and Lewis Base Catalyzed Activation
Asymmetric Induction in Enantioselective Catalysis
Nonclassical Catalyst Substrate Interactions
Chiral Poisoning, Chiral Activation, and Screening Achiral Ligands
Kinetic Resolution
Parallel Kinetic Resolution
Dynamic Kinetic Resolution and Dynamic Kinetic Asymmetric Transformations
Desymmetrization Reactions
Nonlinear Effects, Autocatalysis, and Autoinduction
Bifunctional, Dual, and Multifunctional Catalyst Systems
Asymmetric Catalysis with Enantiopure Substrates: Double Diastereoselection
Multistep Asymmetric Catalysis
Supported Chiral Catalysts
Applications of Asymmetric Catalysis in Synthesis
Appendix: Terms & Enantioselective Processes in Asymmetric Catalysis
Index
Authors
PATRICK J. WALSH is a Professor of Chemistry at University of Pennsylvania, USA
MARISA C. KOZLOWSKI is a Professor of Chemistry at University of Pennsylvania, USA
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