Science, Technology and Medicine in Modern History

Biology, Computing, and the History of Molecular Sequencing

From Proteins to DNA, 1945-2000

Authors: García-Sancho, M.

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About this book

Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.

About the authors

Miguel Garcia-Sancho obtained his Ph.D. at Imperial College London, UK, and has worked at the University of Manchester and Spanish National Research Council (CSIC). He is currently a Chancellor's Fellow at the Department of Science, Technology and Innovation Studies of the University of Edinburgh. His interests lay in the history and social studies of twentieth century biomedicine, as well as science communication and free-lance scientific journalism.

Reviews

"Overall, this book provides a detailed time line of the events from the earliest methodologies to the metagenomic sequencing standard of today, and is a useful resource for anyone interested in the historical angle of DNA sequencing. Highly recommended." - M.C. Pavao, Worcester State College, Choice

"...an invaluable, possibly even essential, addition to the bookshelf of anyone wishing to understand modern biology in all its facets...The author has done a masterful job of integrating information about the way in which different aspects of computer science...have contributed to the development of sequencing." - Neeraja Sankaran, British Journal for the History of Science, 46: 544

"...a revised dissertation, grounded in a remarkable variety of primary sources including corporate records and oral history interviews." - Ruth Schwatz Cowan, American Historical Review, June 2013: 827

"...a timely and informative history of molecular sequencing ... Overall, Garcia-Sancho's book provides a highly readable and insightful analysis of the history of molecular sequencing, one that should be appreciated for its broad synthesis of existing scholarship and its extensive use of historical documents.." - Doogab Yi, History and Philosophy of the Life Sciences

"Supported by an impressive archival and oral research, and by a thorough revision of the secondary literature of the field, García-Sancho´s book is a celebration of what the history of recent and contemporary science can achieve, and for years to come it will remain as an obliged reference not only for historians of science, but for sociologists and all those interested in the detailed development of the industrialized-information society." - Edna Suarez-Diaz, Dynamis


Table of contents (8 chapters)

  • Introduction: An Historical Approach to Sequencing

    García-Sancho, Miguel

    Pages 1-16

  • The Sequence of Insulin and the Configuration of a New Biochemical Form of Work (1943–1962)

    García-Sancho, Miguel

    Pages 21-38

  • From Chemical Degradation to Biological Replication (1962–1977)

    García-Sancho, Miguel

    Pages 39-64

  • Sequencing Software and the Shift in the Practice of Computation

    García-Sancho, Miguel

    Pages 71-90

  • Sequence Databases and the Emergence of ‘Information Engineers’

    García-Sancho, Miguel

    Pages 91-114

Buy this book

eBook $24.99
price for USA
  • ISBN 978-0-230-37093-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $105.00
price for USA
  • ISBN 978-0-230-25032-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $32.00
price for USA
  • ISBN 978-1-349-32122-3
  • Free shipping for individuals worldwide
  • This title is currently reprinting. You can pre-order your copy now.
Softcover $32.00
price for USA
  • ISBN 978-1-137-54332-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.

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Bibliographic Information

Bibliographic Information
Book Title
Biology, Computing, and the History of Molecular Sequencing
Book Subtitle
From Proteins to DNA, 1945-2000
Authors
Series Title
Science, Technology and Medicine in Modern History
Copyright
2012
Publisher
Palgrave Macmillan UK
Copyright Holder
Palgrave Macmillan, a division of Macmillan Publishers Limited
eBook ISBN
978-0-230-37093-7
DOI
10.1057/9780230370937
Hardcover ISBN
978-0-230-25032-1
Softcover ISBN
978-1-349-32122-3
Softcover ISBN
978-1-137-54332-5
Edition Number
1
Number of Pages
XIII, 242
Topics