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Palgrave Macmillan

Clinical Pharmacology & Therapeutics

Proceedings of Plenary Lectures Symposia and Therapeutic Sessions of the First World Conference on Clinical Pharmacology & Therapeutics London, UK, 3–9 August 1980

  • Conference proceedings
  • © 1980

Overview

Editors:
  1. P. Turner
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  2. C. Padgham
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  3. A. Hedges
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Table of contents (65 papers)

  1. Front Matter

    Pages i-xvi
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  3. Environmental and Genetic Factors in Drug Metabolism

    1. Front Matter

      Pages 49-49
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    2. Variability in Human Drug Metabolism

      • A. H. Conney, E. J. Pantuck, C. B. Pantuck, J. G. Fortner, A. P. Alvares, K. E. Anderson et al.
      Pages 51-62

    3. Gene-Environment Interactions in Drug Metabolism

      • E. S. Vesell
      Pages 63-79

    4. Importance of Purification of Hepatic Cytochrome P-450 for Studying Drug Metabolism in Man

      • R. Kato, T. Kamataki
      Pages 80-85

  4. Therapeutics at the Extremes of Age

    1. Front Matter

      Pages 87-87
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    2. Biological Ageing

      • R. D. T. Cape
      Pages 89-97

    3. Drug Metabolism at Various Ages — Young

      • A. Rane
      Pages 98-107

    4. Methodological Problems Associated with Studies of Drug Metabolism in the Elderly

      • R. E. Vestal
      Pages 108-116

    5. Renal Elimination of Drugs at Various Ages

      • A. H. Neims
      Pages 117-123

    6. Responsiveness to Drugs at Extremes of Age

      • K. O’Malley, J. G. Kelly
      Pages 124-131

  5. Alterations in Receptors During Chronic Drug Therapy

    1. Front Matter

      Pages 133-133
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    2. The Effects of Digoxin on Red Cell Digitalis Receptor Function in Man

      • J. K. Aronson
      Pages 135-144

    3. Mechanisms for Regulation of β-Adrenergic Receptor Function in Desensitization

      • R. J. Lefkowitz
      Pages 145-153

    4. Reversal of Pharmacological and Biochemical Effects of Neuroleptic Drugs on Chronic Administration

      • C. D. Marsden, P. Jenner
      Pages 154-157
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Keywords

Bibliographic Information

  • Book Title: Clinical Pharmacology & Therapeutics

  • Book Subtitle: Proceedings of Plenary Lectures Symposia and Therapeutic Sessions of the First World Conference on Clinical Pharmacology & Therapeutics London, UK, 3–9 August 1980

  • Editors: P. Turner, C. Padgham, A. Hedges

  • DOI: https://doi.org/10.1007/978-1-349-05952-2

  • Publisher: Palgrave Macmillan London

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The contributors 1980

  • eBook ISBN: 978-1-349-05952-2Published: 18 June 1980

  • Edition Number: 1

  • Number of Pages: XVI, 576

  • Number of Illustrations: 7 b/w illustrations

  • Topics: Pharmacology/Toxicology

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