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Palgrave Macmillan

Dopaminergic Neurons

  • Book
  • © 1988

Overview

Editors:
  1. P. M. Beart

    1. Clinical Pharmacology and Therapeutics Unit, Austin Hospital, University of Melbourne, Heidelberg, Australia

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  2. G. N. Woodruff

    1. Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Harlow, UK

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    You can also search for this editor in PubMed   Google Scholar

  3. D. M. Jackson

    1. Department of Pharmacology, University of Sydney, Australia

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Satellite Symposia of the Ninth IUPHAR Congress (SSNIC)

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Table of contents (66 chapters)

  1. Front Matter

    Pages i-xvii
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  2. The Status Quo and the Future

    • Joseph G. Cannon
    Pages 1-8

  3. Structure-Activity Relationships for Benzazepines as D1-Specific Dopamine Antagonists

    • Allen Barnett, Robert McQuade, Richard Chipkin
    Pages 9-15

  4. The Development of Potent and Selective D-2 Agonists of the 2-Aminotetralin Group: Their Clinical Applications and their Use in the Isolation of the D-2 Receptor

    • Alan S. Horn, Jan van der Weide, Pieter G. Tepper, Jan B. de Vries, Fokko J. Bosker, Jan Dijk et al.
    Pages 16-21

  5. Dopaminergic Ergots

    • R. Markstein, J. M. Vigouret, A. Enz, D. Coward, A. Jaton, U. Briner
    Pages 22-28

  6. Autoreceptor Agonists

    • HÃ¥kan Wikström
    Pages 29-36

  7. Structural Analyses Predict the Primary Pharmacophore and Secondary Sites for the D2 Receptor

    • Philip M. Beart, David T. Manallack
    Pages 37-42

  8. Structure-Activity Relationship of Tetrahydroprotoberberines on Central Dopamine Receptors: (−)-Stepholidine—a New Antagonist of Dopamine Receptors

    • G. Z. Jin, K. X. Huang, W. D. Le, S. X. Xu
    Pages 43-45

  9. D1 and D2 Dopamine Receptors: Identification by Photoaffinity Labeling and Purification by Affinity Chromatography

    • Marc G. Caron, Susan E. Senogles, Nourdine Amlaiky, Joel G. Berger
    Pages 46-51

  10. D2 Dopamine Receptors: Isolation and Mechanism

    • Philip G. Strange
    Pages 52-58

  11. Intracellular Ionic Changes Induced by Dopamine Receptor Stimulation in Mammotrophs: Evidence for a K+ Channel-linked Dopamine D-2 Receptor

    • M. Memo, A. Valerio, L. Castelletti, M. Pizzi, C. Missale, M. O. Carruba et al.
    Pages 59-68

  12. Dopamine D-2 Receptor Agonists Decrease the Basal Level of Inositol 1,4,5-Trisphosphate in Rat Striatal Slices

    • M. Da Prada, M. Pizzi, A. Valerio, M. Memo, P. F. Spano, W. E. Haefely
    Pages 69-76

  13. D2 Receptor Activation Increases Potassium Conductance in Substantia Nigra Zona Compacta Neurones in vitro

    • M. G. Lacey, N. B. Mercuri, R. A. North
    Pages 77-83

  14. Different States of the Dopamine D1 Receptor: Fact or Fantasy?

    • Peter H. Andersen, Mogens Nielsen, Claus Braestrup
    Pages 84-91

  15. Purification of Receptors Binding Antipsychotics: Comparison with D2-Dopamine Receptor

    • Y. Nishizawa, M. Sato, S. Hayashi, Y. Takahashi
    Pages 92-95

  16. Electrophysiological Investigation of D-1/D-2 Receptor Interactions in the Substantia Nigra and Basal Ganglia

    • J. R. Walters, D. A. Bergstrom, J. H. Carlson, B. G. Weick, H. S. Pan
    Pages 96-102

  17. Biochemical Insights into the D-1/D-2 Receptor Interactions

    • J. C. Stoof
    Pages 103-109

  18. Dopamine D-1 and D-2 Receptor Differentiation Revealed by Behavioural Studies in Rats

    • Jørn Arnt, Klaus Peter Bøgesø, John Hyttel
    Pages 110-116

  19. New Selective D-1 and D-2 Dopamine Receptor Agonists as Further Probes for Behavioural Interactions between D-1 and D-2 Systems

    • John L. Waddington, Angela M. Murray, Kathy M. O’Boyle
    Pages 117-123

  20. Neurobiology of Supersensitive D1 and D2-Dopamine Receptors after 6-Hydroxydopamine Lesions

    • George R. Breese, Hugh E. Criswell, Gary E. Duncan, Thomas J. McCown, Robert A. Mueller
    Pages 124-130
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About this book

The proceedings of the 1987 IUPHAR symposium held in Sydney, Australia are fully documented. Over 100 scientists from 16 countries attended the three-day conference, during which time 68 multi-disciplinary presentations concerning dopamine systems and their regulation were made.

Editors and Affiliations

  • Clinical Pharmacology and Therapeutics Unit, Austin Hospital, University of Melbourne, Heidelberg, Australia

    P. M. Beart

  • Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Harlow, UK

    G. N. Woodruff

  • Department of Pharmacology, University of Sydney, Australia

    D. M. Jackson

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