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Stable Isotopes

Applications in Pharmacology, Toxicology and Clinical Research

  • Book
  • © 1978

Overview

Editors:
  1. T. A. Baillie

    1. Department of Clinical Pharmacology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK

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Table of contents (27 chapters)

  1. Applications in clinical research

    1. Characterisation of bile acid metabolism in man using bile acids labelled with stable isotopes

      • A. F. Hofmann, P. D. Klein
      Pages 189-204

    2. Detection and quantification of stable isotope incorporation by high-resolution mass spectrometry and 13C{2H,1H} nuclear magnetic resonance difference spectroscopy. Utilisation of carbon and hydrogen atoms of ethanol in the biosynthesis of bile acids

      • D. M. Wilson, A. L. Burlingame, S. Evans, T. Cronholm, J. Sjövall
      Pages 205-216

    3. Teratological studies on effects of carbon-13 incorporation into preimplantation mouse embryos on development after implantation in vivo and in vitro

      • H. Spielmann, H.-G. Eibs, U. Jacob, D. Nagel, C. T. Gregg
      Pages 217-225

    4. 13CO2 breath tests in normal and diabetic children following ingestion of 13C-glucose

      • H. Helge, B. Gregg, C. Gregg, S. Knies, I. Nötges-Borgwardt, B. Weber et al.
      Pages 227-234

    5. Studies on catecholamine metabolism in man using in vivo deuterium labelling

      • E. ÄnggÃ¥rd, B. Sjöqvist, T. Lewander
      Pages 235-245

    6. The metabolism of deuterium-labelled p-tyramine in man

      • R. A. D. Jones, C. R. Lee, R. J. Pollitt
      Pages 247-252

    7. Studies in man using semi-tracer doses of deuterated phenylalanine and tyrosine: implications for the investigation of phenylketonuria using the deuterated phenylalanine load test

      • J. A. Hoskins, R. J. Pollitt
      Pages 253-260

    8. Application of chemical ionization mass spectrometry and stable isotopes in studies of α-methyldopa metabolism

      • N. Castagnoli, K. L. Melmon, C. R. Freed, M. M. Ames, A. Kalir, R. Weinkam
      Pages 261-279

    9. The role of prostaglandins in the pathogenesis of human disease: elucidation with stable isotopic methods

      • J. A. Oates, H. W. Seyberth, J. C. Frölich, B. J. Sweetman, J. T. Watson
      Pages 281-287

    10. Application of deuterium labelling in studies of the biosynthesis and metabolism of prostaglandin F2α in man

      • A. R. Brash, M. E. Conolly, G. H. Draffan, P. Tippett, T. A. Baillie
      Pages 289-301

    11. Balance of water, urea and creatinine in peritoneal dialysis

      • R. Medina, H.-L. Schmidt, W. Hoppe, G. Traut
      Pages 303-309

  2. Back Matter

    Pages 311-314
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Keywords

Editors and Affiliations

  • Department of Clinical Pharmacology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK

    T. A. Baillie

Bibliographic Information

  • Book Title: Stable Isotopes

  • Book Subtitle: Applications in Pharmacology, Toxicology and Clinical Research

  • Editors: T. A. Baillie

  • DOI: https://doi.org/10.1007/978-1-349-03328-7

  • Publisher: Palgrave Macmillan London

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Contributors 1978

  • Softcover ISBN: 978-1-349-03330-0Published: 01 January 1978

  • eBook ISBN: 978-1-349-03328-7Published: 17 June 1978

  • Edition Number: 1

  • Number of Pages: XIII, 314

  • Topics: Pharmacology/Toxicology, Imaging / Radiology

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